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In order to assess malaise resulting from radiotherapy, a questionnaire was compiled and administered six times to four groups of cancer patients during a 3-week treatment period. The validity of a malaise scale consisting of four items of the questionnaire was confirmed. The symptoms of malaise, as measured, rapidly increased in magnitude during treatment. Specific physical complaints, as measured with a physical fatigue scale, showed an increase only late in the course of treatment.
KOBASHI-SCHOOT et al. (Sun,) studied this question.