Does electrical stimulation of the periventricular/periaqueductal gray areas reverse orthostatic hypotension in humans?
Electrical stimulation of specific brain regions may offer a novel therapeutic approach for orthostatic hypotension by modulating sympathetic outflow.
Electrical stimulation of the human periventricular/periaqueductal gray areas can reverse orthostatic hypotension. The cause seems to be an increase in sympathetic outflow and in baroreflex sensitivity. This has important implications for future therapies.
Green et al. (Tue,) studied this question.
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