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Crohn's disease is a disabling condition over time. The impact of changing treatment paradigms with increased use of immunosuppressants and biological agents on its natural history is poorly known.
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Laurent Peyrin–Biroulet
University of Rome Tor Vergata
Edward V. Loftus
Ulsan College
Jean‐Frédéric Colombel
Semmelweis University
The American Journal of Gastroenterology
Mayo Clinic
Mayo Clinic in Arizona
WinnMed
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Peyrin‐Biroulet et al. (Tue,) studied this question.
synapsesocial.com/papers/69a602b9272dc2d784053704 — DOI: https://doi.org/10.1038/ajg.2009.579