Oral Poliovirus Vaccine (Sabin) in Czechoslovakia

IN VIEW OF the favorable results of our first field trial of Sabin's live poliovirus vaccine, conducted in Czechoslovakia in winter 1958-1959 in about 140,000 children aged 2 to 6 years,1,2and the results of other, particularly Soviet, authors,3we decided to organize a nation-wide vaccination of the entire child population in the spring of 1960, using live vaccine. Vaccination Program About 3,500,000 children aged 2 months to 14 years and some aged 15 years, i.e., about 93% of Czechoslovakia's child population (Table 1) werevaccinated. The vaccine, prepared from Sabin's attenuated viruses at the Institute for Sera and Vaccines in Prague and supplemented by vaccine procured from the Institute for Poliomyelitis Research in Moscow, was administered in liquid form, about 100,000 TCD50of each type, in a teaspoonful of syrup simplex. Because of lack of time the following schedule of administration of attenuated viruses