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Hippocampal atrophy, while not specific for AD, was a fairly sensitive marker of the pathologic AD stage (particularly among subjects with isolated AD pathology r = -0.63, p = 0.001) and consequent cognitive status.
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Clifford R. Jack
Dennis W. Dickson
Joseph E. Parisi
Neurology
Mayo Clinic
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Jack et al. (Tue,) studied this question.
www.synapsesocial.com/papers/69d80e4633ca018b39ae3328 — DOI: https://doi.org/10.1212/wnl.58.5.750
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