In a cohort of 80 elderly patients on maintenance digoxin, the drug was successfully withdrawn without detriment in 59 patients (74%), indicating that maintenance therapy is often unnecessary.
Observational (n=80)
Digitalis glycosides remain the cornerstone of treatment in cardiac failure. The increasing frequency of toxic effects is a cause for concern. Review of 80 elderly patients receiving digoxin on a maintenance basis, some of whom had toxic effects, shows that in almost three-quarters of the group digoxin was stopped without detriment. Elderly patients on maintenance treatment should be reviewed, and in the absence of a known primary cardiac lesion an attempt should be made to withdraw digoxin.
J. L. C. Dall (Sat,) conducted a observational in Elderly patients on maintenance digoxin (n=80). Withdrawal of digoxin was evaluated on Successful withdrawal of digoxin without recurrence of cardiac decompensation. In a cohort of 80 elderly patients on maintenance digoxin, the drug was successfully withdrawn without detriment in 59 patients (74%), indicating that maintenance therapy is often unnecessary.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: