Does intravenous amiodarone or coronary revascularization suppress or prevent polymorphous ventricular tachycardia in patients with acute myocardial infarction?
Patients with post-myocardial infarction polymorphous ventricular tachycardia
Intravenous amiodarone therapy or coronary revascularization
Suppression or prevention of polymorphous ventricular tachycardia recurrence
Intravenous amiodarone and coronary revascularization are effective strategies for managing post-myocardial infarction polymorphous ventricular tachycardia, which is often driven by recurrent ischemia.
Post-myocardial infarction polymorphous ventricular tachycardia is not consistently related to an abnormally long QT interval, sinus bradycardia, preceding sinus pauses, or electrolyte abnormalities. This arrhythmia has a variable response to class I antiarrhythmics but may be suppressed by intravenous amiodarone therapy. It is often associated with signs or symptoms of recurrent myocardial ischemia. Furthermore, coronary revascularization appears to be effective in preventing the recurrence of polymorphous ventricular tachycardia when associated with recurrent postinfarction angina.
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Christopher L. Wolfe
State University of New York
Carleton Nibley
Anil K. Bhandari
University of Southern California
Circulation
University of California, San Francisco
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Wolfe et al. (Tue,) studied this question.
synapsesocial.com/papers/69d5709875589c71d767dd61 — DOI: https://doi.org/10.1161/01.cir.84.4.1543
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