Does dual-chamber pacing improve stroke-free survival or other clinical outcomes in patients with sinus-node dysfunction compared to ventricular pacing?
Patients with sinus-node dysfunction
Dual-chamber pacing
Ventricular pacing
Stroke-free survivalhard clinical
In patients with sinus-node dysfunction, dual-chamber pacing offers significant symptomatic and clinical improvements over ventricular pacing, despite not improving stroke-free survival.
In sinus-node dysfunction, dual-chamber pacing does not improve stroke-free survival, as compared with ventricular pacing. However, dual-chamber pacing reduces the risk of atrial fibrillation, reduces signs and symptoms of heart failure, and slightly improves the quality of life. Overall, dual-chamber pacing offers significant improvement as compared with ventricular pacing.
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Gervasio A. Lamas
Kerry L. Lee
Michael O. Sweeney
New England Journal of Medicine
Harvard University
University of California, San Francisco
Brigham and Women's Hospital
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Lamas et al. (Thu,) studied this question.
www.synapsesocial.com/papers/69d808af5c3030ff03d18c0e — DOI: https://doi.org/10.1056/nejmoa013040