Why the study?
Does dual-chamber pacing improve stroke-free survival or other clinical outcomes in patients with sinus-node dysfunction compared to ventricular pacing?
Does dual-chamber pacing improve stroke-free survival or other clinical outcomes in patients with sinus-node dysfunction compared to ventricular pacing?
In patients with sinus-node dysfunction, dual-chamber pacing offers significant symptomatic and clinical improvements over ventricular pacing, despite not improving stroke-free survival.
Dual-chamber pacing may reduce AF and symptoms in sinus-node dysfunction; leaves open survival impact and optimal strategy.
In sinus-node dysfunction, dual-chamber pacing does not improve stroke-free survival, as compared with ventricular pacing. However, dual-chamber pacing reduces the risk of atrial fibrillation, reduces signs and symptoms of heart failure, and slightly improves the quality of life. Overall, dual-chamber pacing offers significant improvement as compared with ventricular pacing.
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Lamas et al. (2002) studied this question.
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