Does dual-chamber pacing improve stroke-free survival or other clinical outcomes in patients with sinus-node dysfunction compared to ventricular pacing?
In patients with sinus-node dysfunction, dual-chamber pacing offers significant symptomatic and clinical improvements over ventricular pacing, despite not improving stroke-free survival.
In sinus-node dysfunction, dual-chamber pacing does not improve stroke-free survival, as compared with ventricular pacing. However, dual-chamber pacing reduces the risk of atrial fibrillation, reduces signs and symptoms of heart failure, and slightly improves the quality of life. Overall, dual-chamber pacing offers significant improvement as compared with ventricular pacing.
Lamas et al. (2002) studied this question.