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The protective effect of the Mediterranean dietary pattern was maintained up to 4 years after the first infarction, confirming previous intermediate analyses. Major traditional risk factors, such as high blood cholesterol and blood pressure, were shown to be independent and joint predictors of recurrence, indicating that the Mediterranean dietary pattern did not alter, at least qualitatively, the usual relationships between major risk factors and recurrence. Thus, a comprehensive strategy to decrease cardiovascular morbidity and mortality should include primarily a cardioprotective diet. It should be associated with other (pharmacological?) means aimed at reducing modifiable risk factors. Further trials combining the 2 approaches are warranted.
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Michel de Lorgeril
Patricia Salen
Jean‐Louis Martin
Circulation
Inserm
Centre Hospitalier Universitaire de Saint-Étienne
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Lorgeril et al. (Tue,) studied this question.
www.synapsesocial.com/papers/69cf1457475452f2e7071a91 — DOI: https://doi.org/10.1161/01.cir.99.6.779