August 17, 2011Open Access

Interleukin-36–Receptor Antagonist Deficiency and Generalized Pustular Psoriasis

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Abstract

Aberrant interleukin-36Ra structure and function lead to unregulated secretion of inflammatory cytokines and generalized pustular psoriasis. (Funded by Agence Nationale de la Recherche and Société Française de Dermatologie.).

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Authors

Slaheddine Marrakchi

Hopital Universitaire Hedi Chaker

Philippe Guigue

Inserm

Blair R. Renshaw

EndoGastric Solutions (United States)

Journals

New England Journal of Medicine

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Institutions

University of Cambridge

Inserm

Université Paris Cité

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Marrakchi et al. (Wed,) studied this question.

synapsesocial.com/papers/69d75d8ef182769aa8b8ab40 — DOI: https://doi.org/10.1056/nejmoa1013068

Also consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Pathogenesis and clinical features of psoriasis· 2007 · 2,112 citations
Estimating the age of rare disease mutations: the example of Triple-A syndrome· 2004 · 121 citations
Pathogenesis and therapy of psoriasis· 2007 · 1,752 citations
Generalized pustular psoriasis. A review of 63 cases· 1991 · 25 citations
Generalized pustular psoriasis: strategy for identification of psoriasis susceptibility gene· 2003 · 3 citations

Also consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

Pathogenesis and clinical features of psoriasis· 2007 · 2,112 citations
Estimating the age of rare disease mutations: the example of Triple-A syndrome· 2004 · 121 citations
Pathogenesis and therapy of psoriasis· 2007 · 1,752 citations
Generalized pustular psoriasis. A review of 63 cases· 1991 · 25 citations
Generalized pustular psoriasis: strategy for identification of psoriasis susceptibility gene· 2003 · 3 citations

Interleukin-36–Receptor Antagonist Deficiency and Generalized Pustular Psoriasis

Key Points

Abstract

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Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

Cite this study

Also consider

Also consider