Does a high sensitivity troponin assay with sex specific diagnostic thresholds improve the diagnosis of myocardial infarction in women with suspected acute coronary syndrome?
Implementing sex-specific diagnostic thresholds for high sensitivity troponin assays can double the detection of myocardial infarction in women, identifying a high-risk population that is currently under-diagnosed.
Although having little effect in men, a high sensitivity troponin assay with sex specific diagnostic thresholds may double the diagnosis of myocardial infarction in women and identify those at high risk of reinfarction and death. Whether use of sex specific diagnostic thresholds will improve outcomes and tackle inequalities in the treatment of women with suspected acute coronary syndrome requires urgent attention.
Shah et al. (Wed,) studied this question.