Pathology in Practice

In cooperation with HistoryA 7-year-old 31-kg (68.2-lb) sexually intact male English Bulldog was referred for evaluation of severe expiratory dyspnea that was unresponsive to treatment with furosemide.The dog had a history of idiopathic juvenile epilepsy and was currently receiving treatment with phenobarbital (100 mg, PO, q 12 h) and bromide (400 mg, PO, q 12 h).At the referral evaluation, the emergency care provided included administration of cephalexin (30 mg/kg 13.6 mg/lb, IV, q 12 h), enrofloxacin (5 mg/kg 2.27 mg/lb, IV, q 12 h), beclomethasone dipropionate (aerosol, q 8 h), butorphanol tartrate (0.2 mg/kg 0.09 mg/lb, IM, single administration), oxygen via nasal probe (65 mL/kg 29.5 mL/lb)), and fluid therapy (50 mL/kg/24 h 22.7 mL/ lb/24 h), IV).Despite treatment, the dog developed respiratory arrest 12 hours after admission, and CPR was unsuccessful.