July 1, 2000Open Access
Positive Correlation between Virulence of Pseudomonas aeruginosa Mutants in Mice and Insects
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Abstract
Strain PA14, a human clinical isolate of Pseudomonas aeruginosa, is pathogenic in mice and insects (Galleria mellonella). Analysis of 32 different PA14 mutants in these two hosts showed a novel positive correlation in the virulence patterns. Thus, G. mellonella is a good model system for identifying mammalian virulence factors of P. aeruginosa.
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Authors
G
Georg Jander
Cornell University
L
Laurence G. Rahme
Harvard University
Frederick M. Ausubel
Rutgers, The State University of New Jersey
Journals
Journal of Bacteriology
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Institutions
Harvard University
Massachusetts General Hospital
Burn Institute
References and Citations
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