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Clinical Trials. Allocating Patients to Treatments. Measurement of Treatment Difference. The Design of a Sequential Trial Using the Boundaries Approach. The Analysis of a Sequential Trial. Alternative Approaches to the Design and Analysis of Sequential Clinical Trials. Prognostic Factors. The Comparison of More than Two Treatments. Implementation of Sequential Methods: Some Examples. References. Appendix. Index.
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Harrington et al. (Fri,) studied this question.
synapsesocial.com/papers/6a091cc9266340834eb61bf2 — DOI: https://doi.org/10.2307/2288093
David Harrington
Brown University
John Whitehead
Lancaster City Council
Journal of the American Statistical Association
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