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Lower serum levels of IGF-1 are associated with an increased risk of developing AD dementia and higher levels with greater brain volumes even among middle-aged community-dwelling participants free of stroke and dementia. Higher levels of IGF-1 may protect against subclinical and clinical neurodegeneration.
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Andrew J. Westwood
Bone Cancer Research Trust
Alexa S. Beiser
Preventive Cardiology
Charles DeCarli
Kanazawa University
Neurology
Boston University
University of California, Davis
University Medical Center
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Westwood et al. (Sat,) studied this question.
synapsesocial.com/papers/69d72951faf9bc6d3dbef27b — DOI: https://doi.org/10.1212/wnl.0000000000000382