Daily sedentary time was positively associated with predicted 10-year Hard Coronary Heart Disease risk in mobility-limited older adults (0.04% increase per minute for those with CVD, 95% CI 0.02-0.05).
Cross-Sectional (n=1,170)
Is objectively measured physical activity and sedentary behavior associated with predicted 10-year Hard Coronary Heart Disease risk in mobility-limited older adults?
In mobility-limited older adults, daily sedentary time is positively associated with predicted 10-year coronary heart disease risk, while duration of physical activity is inversely associated with risk.
Effect estimate: 0.04% increase per minute sedentary (with CVD) (95% CI 0.02% to 0.05%)
BACKGROUND: Data are sparse regarding the impacts of habitual physical activity (PA) and sedentary behavior on cardiovascular (CV) risk in older adults with mobility limitations. METHODS AND RESULTS: This study examined the baseline, cross-sectional association between CV risk and objectively measured PA among participants in the Lifestyle Interventions and Independence for Elders (LIFE) study. The relationship between accelerometry measures and predicted 10-year Hard Coronary Heart Disease (HCHD) risk was modeled by using linear regression, stratified according to CVD history. Participants (n=1170, 79±5 years) spent 642±111 min/day in sedentary behavior (ie, 0.05). However, a significant interaction was observed between sex and count frequency (P=0.036) for those without CVD, as counts per minute was related to HCHD risk in women (β=-0.94, -1.48 to -0.41; P<0.001) but not in men (β=-0.14, -0.59 to 0.88; P=0.704). CONCLUSIONS: Daily time spent being sedentary is positively associated with predicted 10-year HCHD risk among mobility-limited older adults. Duration, but not intensity (ie, mean counts/min), of daily PA is inversely associated with HCHD risk score in this population-although the association for intensity may be sex specific among persons without CVD. CLINICAL TRIAL REGISTRATION URL: www.clinicaltrials.gov Unique identifier: NCT01072500.
Fitzgerald et al. (Fri,) conducted a cross-sectional in mobility-limited older adults (n=1,170). Sedentary behavior and physical activity was evaluated on predicted 10-year Hard Coronary Heart Disease (HCHD) risk (0.04% increase per minute sedentary (with CVD), 95% CI 0.02% to 0.05%). Daily sedentary time was positively associated with predicted 10-year Hard Coronary Heart Disease risk in mobility-limited older adults (0.04% increase per minute for those with CVD, 95% CI 0.02-0.05).