November 29, 2006Open Access
View Full PaperA Placebo-Controlled Trial of Pioglitazone in Subjects with Nonalcoholic Steatohepatitis
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Abstract
In this proof-of-concept study, the administration of pioglitazone led to metabolic and histologic improvement in subjects with nonalcoholic steatohepatitis. Larger controlled trials of longer duration are warranted to assess the long-term clinical benefit of pioglitazone. (ClinicalTrials.gov number, NCT00227110 ClinicalTrials.gov .).