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Hydroxyurea and transfusion therapy are strongly recommended for many individuals with SCD. Many other recommendations are based on quality of evidence that is less than high due to the paucity of clinical trials regarding screening, management, and monitoring for individuals with SCD.
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Barbara P. Yawn
University of Minnesota
George R. Buchanan
MIT University
Araba Afenyi‐Annan
University of North Carolina at Chapel Hill
JAMA
Harvard University
Johns Hopkins University
National Institutes of Health
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Yawn et al. (Tue,) studied this question.
synapsesocial.com/papers/69dd4b7b7d97b7e86940cab8 — DOI: https://doi.org/10.1001/jama.2014.10517