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Polymer nanoreactors shown to produce and release antibiotics locally | Synapse

October 5, 2012

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Polymer nanoreactors shown to produce and release antibiotics locally

KLKarolina LangowskaUniversity of Basel CPCornelia G. PalivanUniversity of Basel WMWolfgang MeierUniversity of Basel

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Abstract

We designed and prepared nanoreactors based on a poly(2-methyloxazoline)-block-poly(dimethylsiloxane)-block-poly(2-methyloxazoline (PMOXA-b-PDMS-b-PMOXA) amphiphilic triblock copolymer encapsulating the enzyme penicillin acylase for local and controlled production of antibiotics.

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Langowska et al. (Fri,) studied this question.

synapsesocial.com/papers/69db451474ec1634218359a4 https://doi.org/https://doi.org/10.1039/c2cc36345c

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3Distinct penicillin binding proteins involved in the division, elongation, and shape of Escherichia coli K12.1975 · 980 citations
4Therapeutic Nanoreactors: Combining Chemistry and Biology in a Novel Triblock Copolymer Drug Delivery System2005 · 206 citations
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