July 24, 2013Open Access
Riociguat for the Treatment of Pulmonary Arterial Hypertension
Structured PICO
Does riociguat improve exercise capacity in patients with pulmonary arterial hypertension?
P
Population
Patients with pulmonary arterial hypertension
I
Intervention
Riociguat
O
Outcome
Exercise capacitysurrogate
Riociguat provides significant improvement in exercise capacity for patients with pulmonary arterial hypertension.
Abstract
Riociguat significantly improved exercise capacity and secondary efficacy end points in patients with pulmonary arterial hypertension. (Funded by Bayer HealthCare; PATENT-1 and PATENT-2 ClinicalTrials.gov numbers, NCT00810693 and NCT00863681, respectively.).
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Authors
Hossein Ardeschir Ghofrani
Université Paris-Sud
Nazzareno Galiè
Heart Failure & Transplant
Friedrich Grimminger
Vascular Medicine
Journals
New England Journal of Medicine
Actions
Institutions
University of California, San Diego
Inserm
Imperial College London
References and Citations
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