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The use of I 131 antipyrine for determining coronary blood flow in intact dogs is described. The correlation with the simultaneous nitrous oxide method was 0.91 ω m 0.22. Partition coefficient and tissue equilibration were directly determined (1.04 ω 0.13). The method as applied requires only two minutes of sampling and is adaptable to direct writing methods.
Krasnow et al. (Tue,) studied this question.