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Overall survival following nivolumab treatment in patients with advanced treatment-refractory melanoma compares favorably with that in literature studies of similar patient populations. Responses were durable and persisted after drug discontinuation. Long-term safety was acceptable. Ongoing randomized clinical trials will further assess the impact of nivolumab therapy on overall survival in patients with metastatic melanoma.
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Suzanne L. Topalian
Mario Sznol
David F. McDermott
Journal of Clinical Oncology
Georgetown University
Bristol-Myers Squibb (Germany)
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Topalian et al. (Tue,) studied this question.
www.synapsesocial.com/papers/69d8f7762c87b79b92d186ea — DOI: https://doi.org/10.1200/jco.2013.53.0105