Does the absence of preoperative left ventricular contractile reserve predict the absence of postoperative LVEF recovery in patients with low-gradient aortic stenosis undergoing AVR?
Patients with low-gradient aortic stenosis (AS)
Aortic valve replacement (AVR)
Presence vs absence of preoperative left ventricular contractile reserve on dobutamine stress echocardiography (DSH)
Postoperative ejection fraction (LVEF recovery)surrogate
Surgery (AVR) should not be contraindicated solely based on the absence of contractile reserve in low-gradient AS, as LVEF recovery is still possible.
LVEF increases in the majority of patients with low-gradient AS who survive after AVR. Although the absence of contractile reserve on DSH is related to high operative mortality, it does not predict the absence of LVEF recovery in patients surviving to AVR. These data further support the concept that surgery should not be contraindicated on the basis of absence of contractile reserve alone.
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Jean-Paul Quéré
Jean‐Luc Monin
Franck Lévy
Circulation
Inserm
Clinique Saint-Joseph
Centre Hospitalier de Bretagne Sud
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Quéré et al. (Mon,) studied this question.
www.synapsesocial.com/papers/69effb5c4f6a06657c21e3e1 — DOI: https://doi.org/10.1161/circulationaha.105.568824