Excessive alcohol consumption was present in 24% of patients with severe hypertriglyceridemia and was associated with significantly higher triglyceride levels (P < 0.001).
Observational (n=300)
Does excessive alcohol consumption correlate with higher triglyceride levels in patients with severe hypertriglyceridemia?
Excessive alcohol consumption is a major contributing factor to severe hypertriglyceridemia, especially when combined with obesity and diabetes.
p-value: p=< 0.001
AIMS: This study was conducted to examine the relationship between triglyceride (TG) levels and a history of excessive drinking in patients with severe hypertriglyceridemia (HT). METHODS: Alcohol intake as well as other risk factors associated with HT were searched for in case records of 300 patients known to the laboratory to have had a TG level over 11.3 mmol/l. RESULTS: The majority of severe HT could be attributed to obesity, diabetes mellitus, excessive alcohol consumption or combinations of these. Excessive alcohol intake (over 210 g/week for males; over 140 g/week for females) was recorded for 24% of the total, and for 43% in the highest TG quartile. TG levels were significantly higher in the excessive drinkers (P < 0.001) and in patients with acute pancreatitis (P = 0.001). The incidence of pancreatitis in this cohort was 4% and limited to very high TG levels. CONCLUSION: Excessive alcohol consumption was recorded in a quarter of patients with severe HT. Patients with the combination of obesity, diabetes and alcohol excess are prone to develop extremely high TG values.
Bessembinders et al. (Mon,) conducted a observational in Severe hypertriglyceridemia (n=300). Excessive alcohol consumption vs. Non-excessive alcohol consumption was evaluated on Triglyceride levels (p=< 0.001). Excessive alcohol consumption was present in 24% of patients with severe hypertriglyceridemia and was associated with significantly higher triglyceride levels (P < 0.001).