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Notch ligands presenting artificial 3D thymic microenvironments are created on ICC scaffolds utilizing a layer-by-layer molecular assembly technique (see image). A multicomponent LBL film substitutes the function of thymic stromal cells and successfully supports ex vivo T-cell differentiation of human hematopoietic stem cells. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Lee et al. (Mon,) studied this question.
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