A preoperative chronic disease score >5,000, derived from pharmacy dispensing records, was a strong independent predictor of surgical site infection (adjusted OR 2.6).
Case-Control (n=563)
No
Does the chronic disease score improve the prediction of surgical site infection compared to the ASA score?
A chronic disease score based on preoperative drug dispensing can supplement the NNIS risk index to improve the prediction of surgical site infections.
Effect estimate: OR 2.6 (95% CI 1.5-4.7)
Absolute Event Rate: 28.8% vs 16.1%
p-value: p=0.001
The system used by the National Nosocomial Infection Surveillance (NNIS) program to measure risk of surgical site infection uses a score of 3 on the American Society of Anesthesiologists (ASA)-physical status scale as a measure of underlying illness. The chronic disease score measures health status as a function of age, sex, and 29 chronic diseases, inferred from dispensing of prescription drugs. We studied the relationship between the chronic disease score and surgical site infection and whether the score can supplement the NNIS risk index. In a retrospective comparison of 191 patients with surgical site infection and 378 uninfected controls, the chronic disease score and ASA score were highly correlated. The chronic disease score improved prediction of infection by the NNIS risk index and augmented the ASA score for risk adjustment.
Kaye et al. (Mon,) conducted a case-control in Surgical site infection (n=563). Chronic disease score >5,000 vs. Chronic disease score <5,000 was evaluated on Surgical site infection within 30 days after surgery (OR 2.6, 95% CI 1.5-4.7, p=0.001). A preoperative chronic disease score >5,000, derived from pharmacy dispensing records, was a strong independent predictor of surgical site infection (adjusted OR 2.6).