Does echocardiographic evaluation identify preclinical disease in asymptomatic relatives of patients with dilated cardiomyopathy?
Asymptomatic relatives of patients with dilated cardiomyopathy
Echocardiographic evaluation
Identification of treatable asymptomatic dilated cardiomyopathy, left ventricular enlargement, and depressed fractional shorteningsurrogate
Echocardiographic screening of asymptomatic relatives of patients with dilated cardiomyopathy is recommended as it successfully identifies preclinical disease and risk for progression.
Treatable asymptomatic dilated cardiomyopathy was identified in 4.6% of asymptomatic relatives. In addition, left ventricular enlargement and depressed fractional shortening were common in asymptomatic relatives of patients with dilated cardiomyopathy and were associated with a statistically significant medium-term risk for disease progression. Evaluation of relatives of patients with cardiomyopathy is recommended.
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Niall Mahon
Heart Failure & Transplant
Ross T. Murphy
Trinity College Dublin
Calum A. MacRae
General Cardiology
Annals of Internal Medicine
Massachusetts General Hospital
University of Padua
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Mahon et al. (Tue,) studied this question.
synapsesocial.com/papers/69d5724e75589c71d767e6f2 — DOI: https://doi.org/10.7326/0003-4819-143-2-200507190-00009