Sports-related sudden cardiac death was dramatically less common in women compared with men, particularly in the 45- to 54-year range (RR 0.033; 95% CI 0.015-0.075).
Observational (n=820)
Yes
What are the incidence, characteristics, and outcomes of sports-related sudden cardiac death in women compared to men?
Sports-related sudden cardiac death is significantly less common in women than men, and women have a higher likelihood of successful resuscitation and lower rates of structural heart disease.
Effect estimate: RR 0.033 (95% CI 0.015-0.075)
BACKGROUND: No specific data are available on characteristics and outcome of sudden cardiac death (SCD) during sport activities among women in the general population. METHODS AND RESULTS: From a prospective 5-year national survey, involving 820 subjects 10 to 75 years old who presented with SCD (resuscitated or not) during competitive or recreational sport activities, 43 (5.2%) such events occurred in women, principally during jogging, cycling, and swimming. The level of activity at the time of SCD was moderate to vigorous in 35 cases (81.4%). The overall incidence of sport-related SCD, among 15- to 75-year-old women, was estimated as 0.59 (95% confidence interval CI, 0.39-0.79) to 2.17 (95% CI, 1.38-2.96) per year per million female sports participants for the 80th and 20th percentiles of reporting districts, respectively. Compared with men, the incidence of SCDs in women was dramatically lower, particularly in the 45- to 54-year range (relative risk, 0.033; 95% CI, 0.015-0.075). Despite similar circumstances of occurrence, survival at hospital admission (46.5%; 95% CI, 31.0-60.0) was significantly higher than that for men (30.0%; 95% CI, 26.8-33.2; P=0.02), although this did not reach statistical significance for hospital discharge. Favorable neurological outcomes were similar (80%). Cause of death seemed less likely to be associated with structural heart disease in women compared with men (58.3% versus 95.8%; P=0.003). CONCLUSIONS: Sports-related SCDs in women participants seems dramatically less common (up to 30-fold less frequent) compared with men. Our results also suggest a higher likelihood of successful resuscitation as well as less frequency of structural heart disease in women compared with men.
Marijon et al. (Tue,) conducted a observational in Sudden cardiac death during sports (n=820). Female sex vs. Male sex was evaluated on Incidence of sport-related sudden cardiac death (45- to 54-year range) (RR 0.033, 95% CI 0.015-0.075). Sports-related sudden cardiac death was dramatically less common in women compared with men, particularly in the 45- to 54-year range (RR 0.033; 95% CI 0.015-0.075).
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