Pulse rate variability accurately measures heart rate variability during normal sleep breathing but does not precisely reflect it during sleep disordered breathing events (p<0.01).
Observational (n=51)
Does pulse rate variability (PRV) accurately reflect heart rate variability (HRV) during obstructive sleep apnea?
PRV provides accurate inter-pulse variability under normal breathing but does not precisely reflect HRV during sleep disordered breathing.
Effect estimate: r>0.95
p-value: p=<0.01
We investigate whether pulse rate variability (PRV) extracted from finger photo-plethysmography (Pleth) waveforms can be the substitute of heart rate variability (HRV) from RR intervals of ECG signals during obstructive sleep apnea (OSA). Simultaneous measurements (ECG and Pleth) were taken from 29 healthy subjects during normal (undisturbed sleep) breathing and 22 patients with OSA during OSA events. Highly significant (pr>0.95) were found between heart rate (HR) and pulse rate (PR). Bland-Altman plot of HR and PR shows good agreement (<5% difference). Comparison of 2 min recording epochs demonstrated significant differences (p<0.01) in time, frequency domains and complexity analysis, between normal and OSA events using PRV as well as HRV measures. Results suggest that both HRV and PRV indices could be used to distinguish OSA events from normal breathing during sleep. However, several variability measures (SDNN, RMSSD, HF power, LF/HF and sample entropy) of PR and HR were found to be significantly (p<0.01) different during OSA events. Therefore, we conclude that PRV provides accurate inter-pulse variability to measure heart rate variability under normal breathing in sleep but does not precisely reflect HRV in sleep disordered breathing.
Khandoker et al. (Mon,) conducted a observational in Obstructive sleep apnea (n=51). Pulse rate variability (PRV) from finger photo-plethysmography vs. Heart rate variability (HRV) from ECG was evaluated on Correlation and agreement between PRV and HRV indices (r>0.95, p=<0.01). Pulse rate variability accurately measures heart rate variability during normal sleep breathing but does not precisely reflect it during sleep disordered breathing events (p<0.01).