September 2, 2010Open Access
Power and instrument strength requirements for Mendelian randomization studies using multiple genetic variants
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Resumen
The feasibility of well-powered, unbiased MR studies will depend upon the amount of variance in the exposure that can be explained by known genetic factors and the 'strength' of the IV set derived from these genetic factors.
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Authors
B
Brandon L. Pierce
Chicago Department of Public Health
H
Habibul Ahsan
Dartmouth College
Tyler J. VanderWeele
Pepperdine University
Journals
International Journal of Epidemiology
Actions
Institutions
Harvard University
University of Chicago
Chicago Department of Public Health
References and Citations
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