A relative change in longitudinal strain >1.2% during handgrip before PCI detected significant coronary stenosis with 80% sensitivity, 66% specificity, and an AUC of 0.77 (P<0.001).
Observational (n=35)
Does longitudinal speckle-tracking strain combined with isometric handgrip stress test detect ischemic myocardial segments in patients with stable angina pectoris?
Longitudinal speckle-tracking strain combined with an isometric handgrip stress test can detect ischemic myocardial segments and predict regional contraction improvement after revascularization.
Effect estimate: AUC 0.77
p-value: p=<0.001
BACKGROUND: Isometric handgrip stress test is a simple method for detecting coronary artery disease (CAD). However, the value of this method alone is limited by relatively low sensitivity. This study thus aimed to investigate the usefulness of two-dimensional speckle-tracking strain combined with handgrip for CAD patients. METHOD: We studied 35 patients with stable angina pectoris who underwent percutaneous coronary intervention (PCI). Longitudinal (L-ɛ) and transverse peak systolic (T-ɛ) strains were measured from three standard apical views before and 1 month after PCI. Segments corresponded to perfusion territories of coronary arteries were divided into two groups based on coronary angiography results: stenotic (S) and nonstenotic (NS) segment. RESULTS: L-ɛ in S segments increased significantly after PCI, from -15.8% to -17.6% (P 1.2% during handgrip before PCI could detect significant coronary stenosis with a sensitivity of 80%, specificity of 66%, and area under the curve of 0.77 (P < 0.001). On the other hand, no significant changes were observed in either T-ɛ segments during handgrip either before or after PCI. CONCLUSION: Longitudinal speckle-tracking strain combined with handgrip may constitute a valuable tool for detection of ischemic myocardial segments and prediction of improvement of regional contraction after revascularization.
Ryo et al. (Tue,) conducted a observational in Stable angina pectoris (n=35). Two-dimensional speckle-tracking strain combined with isometric handgrip stress test vs. Nonstenotic segments was evaluated on Detection of significant coronary stenosis (AUC 0.77, p=<0.001). A relative change in longitudinal strain >1.2% during handgrip before PCI detected significant coronary stenosis with 80% sensitivity, 66% specificity, and an AUC of 0.77 (P<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: