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We undertook a prospective study to quantitate Burkholderia pseudomallei in blood, urine, respiratory secretions, and pus corrected obtained from 414 patients with melioidosis. The median was count 1.1, 1.5 x 10(4), 1.1 x 10(5), and 1.1 x 10(7) CFU/mL in these sample types, respectively. This provides important insights into the likely feasibility of future studies such as expression microarray analysis using clinical material.
Wuthiekanun et al. (Thu,) studied this question.