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October 4, 2013EP Europace

Role of electrical storm as a mortality and morbidity risk factor and its clinical predictors: a meta-analysis

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Why the study?

Is electrical storm a risk factor for mortality and morbidity, and what are its clinical predictors?

Population

Patients at risk for or experiencing electrical storm, including those with implantable…

Comparison

Electrical storm (as an exposure/risk factor) vs Absence of electrical storm

Design

Meta-analysis

Authors

FGFederico GuerraMSMatilda ShkozaLSL. Scappini

Discussion

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Overview

Supports intensified monitoring after electrical storm; confirms its composite prognostic impact across studies.

Key Points

  • To evaluate the association between electrical storm and adverse cardiac outcomes while identifying clinical predictors of electrical storm occurrence.
  • Conducted a systematic review and meta-analysis of studies evaluating mortality, morbidity, and patient-level risk factors associated with electrical storm.
  • Electrical storm is a strong mortality risk factor associated with an increased composite risk of all-cause death, heart transplantation, and hospitalization for heart failure.
  • Secondary prevention implantable cardioverter-defibrillators, monomorphic ventricular tachycardia triggers, lower ejection fraction, and class I anti-arrhythmic drug therapy are significant clinical predictors of electrical storm.

Structured PICO

Is electrical storm a risk factor for mortality and morbidity, and what are its clinical predictors?

P
Population
Patients at risk for or experiencing electrical storm, including those with implantable cardioverter-defibrillators
I
Intervention
Electrical storm (as an exposure/risk factor)
C
Comparator
Absence of electrical storm
O
Outcome
Mortality and combined risk of death, heart transplantation, and hospitalization for heart failurehard clinical

Electrical storm is a significant predictor of mortality and heart failure morbidity, and can be predicted by factors such as secondary prevention ICDs, monomorphic VT, lower ejection fraction, and class I anti-arrhythmic drug therapy.

Cite This Study

Guerra et al. (2013) studied this question.

synapsesocial.com/papers/69d56c3975589c71d767ccf8https://doi.org/10.1093/europace/eut304
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