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Moringa oleifera leaves have traditionally been used in Ayurvedic medicine for their antihypertensive activity. Preliminary studies in our laboratory indicated that a water extract of leaves of this tree is efficacious in reducing the chronotropic and inotropic effects on the isolated frog heart. The alkaloids obtained by the fractionation of the water extract of the leaves of M. oleifera, converted into their salt form, were tested for their activity on the isolated frog heart. The total alkaloidal salts were found to have a negative inotropic effect on the frog heart. This activity was further characterised by testing it on the isolated guinea pig ileum.
Dangi et al. (Tue,) studied this question.
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