Renal sympathetic nerve ablation resulted in a progressive and sustained reduction of systemic blood pressure in a hemodialysis patient with refractory hypertension.
Case Report (n=1)
Does renal sympathetic nerve ablation reduce systemic blood pressure in a haemodialysis patient with refractory hypertension?
Renal sympathetic nerve ablation may be a safe and feasible option for reducing blood pressure in haemodialysis patients with refractory hypertension.
Haemodialysis patients show sympathetic hyperactivity. Hyperactivation of the sympathetic nervous system aggravates hypertension and it is related to left ventricular hypertrophy, heart failure, arrhythmias and atherogenesis. We report the first use of renal sympathetic nerve ablation for correction of uncontrolled hypertension in an end-stage renal disease patient on maintenance dialysis. We observed a progressive and sustained reduction of systemic blood pressure. Our case demonstrates the safety, the feasibility and the efficacy of this procedure. These findings suggest, however, that further clinical trials are needed into renal nerve radiofrequency ablation therapy for the treatment of hypertension and for the improvement of cardiovascular prognosis in this high-risk patient group.
Daniele et al. (Thu,) conducted a case report in Refractory hypertension in end-stage renal disease (n=1). Renal sympathetic nerve ablation was evaluated on Systemic blood pressure. Renal sympathetic nerve ablation resulted in a progressive and sustained reduction of systemic blood pressure in a hemodialysis patient with refractory hypertension.
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