Does the Modelflow method using Portapres reliably estimate relative changes in cardiac output compared to Doppler echocardiography during submaximal exercise in healthy young humans?
The Modelflow method using Portapres provides a reliable non-invasive estimation of relative changes in cardiac output during submaximal exercise in healthy young humans.
The Modelflow-estimated cardiac output correlated significantly with the simultaneous estimates by the Doppler method in all subjects (r = 0.87, P < 0.0001) and the SE of estimation was 1.93 L min-1. Correlation coefficients in each subject ranged from 0.91 to 0.98. Although the Modelflow method overestimated cardiac output, the errors between two estimates were not significantly different among the exercise levels. These results suggest that the Modelflow method using Portapres could provide a reliable estimation of the relative change in cardiac output non-invasively and continuously during submaximal exercise in healthy young humans, at least in terms of the relative changes in cardiac output.
Sugawara et al. (Mon,) studied this question.