The edge-to-edge technique for mitral regurgitation repair resulted in a hospital mortality of 1.6%, with an overall survival of 92% and 95% freedom from reoperation at 6 years.
Cohort (n=121)
Mitral regurgitation (n=121)
Edge-to-edge (E-to-E) technique
Overall survival at 6 years
OBJECTIVE: Repair of mitral regurgitation (MR) is more demanding in case of prolapse of the anterior leaflet, posterior leaflet with calcified annulus, or prolapse of both leaflets. We evaluated a repair which consists of anchoring the free edge of the prolapsing leaflet to the corresponding free edge of the facing leaflet: the 'edge-to-edge' (E-to-E) technique. The correction results in a double orifice valve when the prolapse is in the middle portion of the leaflet and in a smaller valve orifice when the prolapse is close to a commissure. METHODS: Out of 432 patients with MR submitted to valve repair between January 1991 and September 1997, 121 (mean age 56 +/- 15.8 years) underwent E-to-E correction. The most prevalent etiology was degenerative disease (82 patients, 68%). The mechanism of MR was anterior leaflet prolapse (61 patients), posterior leaflet prolapse (24 patients), prolapse of both leaflets (28 patients) and other complex mechanisms (8 patients). In 72 patients, a double orifice was created, the paracommissural repair was done in 49 patients. RESULTS: Hospital mortality was 1.6%. Overall survival was 92 +/- 3.1% at 6 years with 95 +/- 4.8% freedom from reoperation. Mortality was unrelated to the type of repair. Mitral stenosis was never observed after the correction. At the follow-up (mean 2.2 +/- 1.5 years), all patients but 15 are class I or II. Symptoms at the follow-up are not related to residual MR. CONCLUSIONS: Midterm results of this alternative repair technique are promising, considering the high prevalence of complex anatomical lesions. The technique is simple, easily reproducible and rapidly feasible also when mitral exposure is suboptimal.
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Francesco Maisano
Structural Heart Disease
Lucia Torracca
Interventional / Structural Cardiology
Michele Oppizzi
Heart Failure & Transplant
European Journal of Cardio-Thoracic Surgery
Vita-Salute San Raffaele University
University of Brescia
IRCCS Ospedale San Raffaele
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Maisano et al. (Sun,) conducted a cohort in Mitral regurgitation (n=121). Edge-to-edge (E-to-E) technique was evaluated on Overall survival at 6 years. The edge-to-edge technique for mitral regurgitation repair resulted in a hospital mortality of 1.6%, with an overall survival of 92% and 95% freedom from reoperation at 6 years.
synapsesocial.com/papers/6a05124670c113c9996a632c — DOI: https://doi.org/10.1016/s1010-7940(98)00014-1