November 1, 2002Open Access
View Full PaperQuickTree: building huge Neighbour-Joining trees ofprotein sequences
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Abstract
Abstract Summary: We have written a fast implementation of the popular Neighbor-Joining tree building algorithm. QuickTree allows the reconstruction of phylogenies for very large protein families (including the largest Pfam alignment containing 27000 HIV GP120 glycoprotein sequences) that would be infeasible using other popular methods. Availability: The source-code for QuickTree, written in ANSI~C, is freely available via the world wide web at http://www.sanger.ac.uk/Software/analysis/quicktree Contact: klh@sanger.ac.uk * To whom correspondence should be addressed.