Does primary percutaneous coronary intervention reduce mortality, reinfarction, and stroke compared to fibrinolytic therapy in patients with ST-segment-elevation myocardial infarction?
Primary PCI provides short-term benefits in mortality, reinfarction, and stroke over fibrinolytic therapy in STEMI, with long-term benefits confirmed in RCTs but not observational studies.
Compared with fibrinolytic therapy, primary percutaneous coronary intervention was associated with short-term reductions in mortality, reinfarction, and stroke in ST-segment-elevation myocardial infarction. Primary percutaneous coronary intervention was associated with long-term reductions in mortality and reinfarction in RCTs, but there was no conclusive evidence for a long-term benefit in mortality and reinfarction in observational studies.
Huynh et al. (Tue,) studied this question.