Age-normalized relative wall thickness identified a significantly higher prevalence of concentric left ventricular geometry in hypertensive patients compared to the traditional cutoff (34% vs 22%, P<0.0001).
Cross-Sectional (n=1,097)
Does age-normalized relative wall thickness improve the identification of concentric left ventricular geometry compared to traditional cutoffs in hypertensive patients?
Age-normalized relative wall thickness cutoffs identify a higher prevalence of concentric left ventricular geometry in hypertensive patients compared to traditional unadjusted cutoffs.
Tasa de eventos absoluta: 34% vs 22%
valor p: p=<0.0001
There might be limitations in identifying concentric left ventricular (LV) geometry by ratio of diastolic posterior wall thickness (WT(p)) to cavity radius, defined as relative wall thickness (RWT(p)). This study has been designed to evaluate age effects on RWT(p). WT(p), mean of septal thickness and WT(p) (WT(m)), and cavity radius were cross-sectionally evaluated in 766 1- to 85-year-old, normotensive, nonobese subjects and 331 hypertensive Italians (used as a test series). RWT(p) > or =0.43 defined "traditional" concentric LV geometry. The ratios WT(m)/radius (RWT(m)) and RWT(p) increased by 0.005 and 0.006 per year of age in the age stratum up to 17 years and by 0.002 in the older age stratum (18 years or older; all P0.41 or RWT(p) >0.40. Further studies are required to establish prognostic implications of our findings.
Simone et al. (Tue,) conducted a cross-sectional in Concentric left ventricular geometry (n=1,097). Age-normalized relative wall thickness vs. Traditional relative wall thickness cutoff was evaluated on Identification of concentric LV geometry in hypertensive subjects (p=<0.0001). Age-normalized relative wall thickness identified a significantly higher prevalence of concentric left ventricular geometry in hypertensive patients compared to the traditional cutoff (34% vs 22%, P<0.0001).