Does the addition of brachial FMD to the Framingham Risk Score improve the prediction and risk classification of incident cardiovascular events in population-based adults?
Brachial FMD improves cardiovascular risk reclassification when added to the Framingham Risk Score, despite not improving overall discrimination.
Brachial FMD is a predictor of incident cardiovascular events in population-based adults. Even though the addition of FMD to the FRS did not improve discrimination of subjects at risk of CVD events in receiver operating characteristic analysis, it improved the classification of subjects as low, intermediate, and high CVD risk compared with the FRS.
Yeboah et al. (Tue,) studied this question.