Eplerenone, a selective aldosterone blocker, in mild-to-moderate hypertension

Structured PICO

Does eplerenone 50 to 400 mg once daily reduce blood pressure in patients with mild-to-moderate hypertension?

Population

Patients with mild-to-moderate hypertension

Intervention

Eplerenone 50 to 400 mg once daily

Outcome

Blood pressure reduction during a 24-h periodsurrogate

Eplerenone 50 to 400 mg once daily is effective and well tolerated for blood pressure reduction in mild-to-moderate hypertension.

Abstract

Eplerenone doses of 50 to 400 mg once daily are well tolerated and effective in reducing BP in patients with mild-to-moderate hypertension during a 24-h period.

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