The Pan American Regional Poliomyelitis Laboratory Network maintained high performance through comprehensive training, continuous monitoring, and close integration of field and laboratory surveillance.
The Pan American Regional Poliomyelitis Laboratory Network successfully supported the eradication of wild poliovirus in the Americas through standardized diagnostic procedures and close integration with field epidemiology.
The Pan American Regional Poliomyelitis Laboratory Network, developed to support the program to eradicate indigenous wild poliovirus transmission in the Americas, included 10 laboratories, distributed in eight countries in the Americas, organized according to the diagnostic procedures they regularly performed. All laboratories isolated and typed virus in stool specimens, several did intratypic differentiation by nucleic acid probe hybridization, and 2 sequenced wild poliovirus isolates for molecular epidemiologic studies. High performance of the network was maintained through comprehensive training of virologists, continuous monitoring of laboratory performance, and prompt investigation of problems. Recommended field and laboratory procedures were regularly reviewed and revised to optimize sensitivity, specificity, and diagnostic efficiency. Close integration of field and laboratory surveillance was achieved through frequent meetings between virologists and epidemiologists, effective communication of program priorities, and the distribution of weekly surveillance reports.
Pinheiro et al. (Sat,) conducted a review in Wild Poliovirus. Pan American Regional Poliomyelitis Laboratory Network was evaluated. The Pan American Regional Poliomyelitis Laboratory Network maintained high performance through comprehensive training, continuous monitoring, and close integration of field and laboratory surveillance.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: