June 25, 2014Open Access
Atrial Fibrillation in Patients with Cryptogenic Stroke
Structured PICO
Does 30-day noninvasive ambulatory ECG monitoring improve the detection of atrial fibrillation in patients ≥55 years with recent cryptogenic stroke or TIA compared to short-duration monitoring?
P
Population
Patients 55 years of age or older with a recent cryptogenic stroke or transient ischemic attack (TIA)
I
Intervention
Noninvasive ambulatory ECG monitoring for a target of 30 days
C
Comparator
Standard practice of short-duration ECG monitoring
O
Outcome
Detection of atrial fibrillationsurrogate
In patients ≥55 years with recent cryptogenic stroke or TIA, 30-day ambulatory ECG monitoring significantly increases the detection of paroxysmal atrial fibrillation and subsequent anticoagulant use compared to standard short-duration monitoring.
Abstract
Among patients with a recent cryptogenic stroke or TIA who were 55 years of age or older, paroxysmal atrial fibrillation was common. Noninvasive ambulatory ECG monitoring for a target of 30 days significantly improved the detection of atrial fibrillation by a factor of more than five and nearly doubled the rate of anticoagulant treatment, as compared with the standard practice of short-duration ECG monitoring. (Funded by the Canadian Stroke Network and others; EMBRACE ClinicalTrials.gov number, NCT00846924.).
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Authors
D
David J. Gladstone
Western University
M
Melanie Spring
St. Michael's Hospital
Paul Dorian
Electrophysiology
Journals
New England Journal of Medicine
Actions
Institutions
University of Toronto
University of British Columbia
McGill University
References and Citations
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