May 19, 2004
View Full PaperCardiac-Resynchronization Therapy with or without an Implantable Defibrillator in Advanced Chronic Heart Failure
Key Result
Cardiac-resynchronization therapy significantly reduces mortality in advanced heart failure patients when combined with an implantable defibrillator.
Structured PICO
Does cardiac-resynchronization therapy with or without an implantable defibrillator reduce the combined risk of death or hospitalization and mortality in patients with advanced heart failure and a prolonged QRS interval?
P
Population
Patients with advanced chronic heart failure and a prolonged QRS interval
I
Intervention
Cardiac-resynchronization therapy with or without an implantable defibrillator
O
Outcome
Combined risk of death from any cause or first hospitalization, and mortalitycomposite
In patients with advanced heart failure and a prolonged QRS interval, cardiac-resynchronization therapy reduces death or hospitalization, and adding a defibrillator further reduces mortality.
Main Result
Absolute Event Rate: 0% vs 0%
Abstract
In patients with advanced heart failure and a prolonged QRS interval, cardiac-resynchronization therapy decreases the combined risk of death from any cause or first hospitalization and, when combined with an implantable defibrillator, significantly reduces mortality.