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One year of oral cyclophosphamide in patients with symptomatic scleroderma-related interstitial lung disease had a significant but modest beneficial effect on lung function, dyspnea, thickening of the skin, and the health-related quality of life. The effects on lung function were maintained through the 24 months of the study.
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Donald P. Tashkin
Robert M. Elashoff
Philip J. Clements
New England Journal of Medicine
Johns Hopkins University
University of California, Los Angeles
University of California, San Francisco
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Tashkin et al. (Wed,) studied this question.
www.synapsesocial.com/papers/69da21d00f778bd2e4684288 — DOI: https://doi.org/10.1056/nejmoa055120