Is percutaneous hepatic vein isolation using a double-balloon catheter feasible and safe for administering high-dose hepatic arterial infusion chemotherapy in unresectable liver tumors?
Percutaneous hepatic vein isolation using a double-balloon catheter is feasible and safe, potentially allowing for dose-intensification strategies in treating unresectable liver tumors.
The use of a double-balloon catheter to isolate and detoxify hepatic venous blood during intraarterial therapy is technically feasible, safe, and allows administration of large doses of intrahepatic chemotherapy at short intervals. This approach should allow new dose-intensification strategies to increase tumor responses in primary and metastatic liver tumors.
Ravikumar et al. (Thu,) studied this question.