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Inconsistencies in the preparation of histology slides make it difficult to perform quantitative analysis on their results. In this paper we provide two mechanisms for overcoming many of the known inconsistencies in the staining process, thereby bringing slides that were processed or stored under very different conditions into a common, normalized space to enable improved quantitative analysis.
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Marc Macenko
Marc Niethammer
J. S. Marron
University of North Carolina at Chapel Hill
North Carolina State University
UNC Lineberger Comprehensive Cancer Center
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Macenko et al. (Mon,) studied this question.
www.synapsesocial.com/papers/69d90a3a099cd0a57a9f55bd — DOI: https://doi.org/10.1109/isbi.2009.5193250
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