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β-Cell Growth and Regeneration: Replication Is Only Part of the Story | Synapse

September 28, 2010Open Access

β-Cell Growth and Regeneration: Replication Is Only Part of the Story

Key Points

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Abstract

I am accordingly of the opinion that the normal regulation of islet content in the pancreas is by interstitial growth

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Cite This Study

Bonner‐Weir et al. (Tue,) studied this question.

synapsesocial.com/papers/6a218449cdf8429e7e5fc40c https://doi.org/https://doi.org/10.2337/db10-0084

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Compensatory Growth of Pancreatic β-Cells in Adult Rats After Short-Term Glucose Infusion1989 · 448 citations
2The regenerative capacity of the pancreas in duct-ligated rats1979 · 31 citations
3Further quantitative structural studies of the pancreatic islet parenchyma in rats with duct ligation.1971 · 10 citations
4Combination Therapy with Glucagon-Like Peptide-1 and Gastrin Induces β-Cell Neogenesis from Pancreatic Duct Cells in Human Islets Transplanted in Immunodeficient Diabetic Mice2008 · 66 citations
5Pancreatic Exocrine Duct Cells Give Rise to Insulin-Producing β Cells during Embryogenesis but Not after Birth2009 · 486 citations